Found 35 matching trials
SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients PHASE2 Open label multicentric randomized phase II trial, using high throughput ge...
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Centre Hospitalier Henri Duffau
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Study of Selumetinib (MK-5618) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (MK-5618-001) PHASE1 This study will examine the safety, pharmacokinetics, and efficacy of escal...
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City of Hope National Medical Center ( Site 0004)
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AZD6244 (ARRY-142886) Solid Oral Dosage Formulation in Participants With Advanced Solid Malignancies PHASE1 The primary purpose of the study is to assess the safety, tolerability and ...
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Active Not Recruiting
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Randomised Study to Compare the Efficacy of AZD6244 vs TMZ PHASE2 The primary purpose of this study is to compare the efficacy of AZD6244 (AR...
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To Assess the Effects of Single Oral Dose of Selumetinib [AZD6244; ARRY-142886] [Hyd-Sulfate]), on QTc Interval in Healthy Male Volunteers PHASE1 Study to assess the effect of Selumetinib \[AZD6244; ARRY-142886\] \[Hyd-Su...
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Selumetinib in Combination With Gefitinib in NSCLC Patients PHASE1 This is an open-label, non-randomized, multicenter phase Ib/II study, which...
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National Cheng Kung University Hospital
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To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers PHASE1 Study to assess the effect of Rifampicin on the pharmacokinetics of Selumet...
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Temsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV PHASE2 The purpose of this study is to find out how often two investigational drug...
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H. Lee Moffitt Cancer Center and Research Institute
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A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN) PHASE1 A Phase 1 Open Label Study to Assess the Safety, Tolerability, Pharmacokine...
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Active Not Recruiting
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Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC PHASE3 The purpose of this study is to assess the efficacy of selumetinib in combi...
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Active Not Recruiting
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